INSTITUT FÜR PHARMAKOLOGIE UND TOXIKOLOGIE

2020 - 2022

2022

Demidova, A., Kahl, E., Fendt, M.:
Orexin deficiency affects sensorimotor gating and its amphetamine-induced impairment.
Prog Neuropsychopharamcol Biol Psychiatry (2022) 116: 110517. DOI: 10.1016/j.pnpbp.2022.110517

Durairaja, A., Steinecke, C.S., Fendt, M.:
Intracerebroventricular infusion of the selective orexin 1 receptor antagonist SB-334867 impairs cognitive flexibility in a sex-dependent manner.
Behav Brain Res (2022) 424: 113791. DOI: 10.1016/j.bbr.2022.113791

Bicakci, A. O., Sarkar, M., Chang, Y-H, Kahl, E., Ragazzi, L., Moldes-Anaya, A., Fendt, M.:
Anxiolytic-like effects of the positive GABAB receptor modulator GS39783 correlate with mice’s individual basal anxiety and stress reactivity.
Pharmaceuticals (2022) 15: 233. DOI: 10.3390/ph15020233

Musa Itopa Yakubu, Nuhu Mohammed Danjuma, Mohammed Garba Magaji, Sani Malami, Axel Becker, Medinat Yakubu Abbas, Ben Ahmed Chindo:
Co-administration of Zingiber officinale Extract and Sodium Valproate Ameliorates Seizure Severity, Cognitive Deficit, and Neuronal Cell Loss in Pentylenetetrazole-kindled Mice.
OBM Integrative and Complementary Medicine (2022) Volume 7, Issue 1. DOI: 10.21926/obm.icm.2201013

 

2021

Kreutzmann, J. C., Marin, M.-F., Fendt, M., Milad, M. R., Ressler, K., Jovanovic, T.:
Unconditioned response to an aversive stimulus as predictor of response to conditioned fear and safety: a cross-species study.
Behav Brain Res 402 (2021): 113105.  DOI:10.1016/j.bbr.2020.113105

Faesel, N., Kolodziejczyk, M. H., Koch, M., Fendt, M.:
Orexin deficiency affects sociability and the acquisition, expression, and extinction of conditioned social fear.
Brain Res 1751 (2021): 147199. DOI: 10.1016/j.brainres.2020.147199

Soleimanpour, E., Bergado Acosta, J.R., Landgraf, P., Mayer, D., Dankert, E., Dieterich, D.C., Fendt, M.:
Regulation of CREB phosphorylation in nucleus accumbens after relief conditioning.
Cells 10 (2021): 238. DOI: 10.3390/cells10020238

Kreutzmann, J. C., Fendt, M.: 
Intranasal oxytocin compensates for estrus cycle-specific reduction of conditioned safety memory in rats: implications for psychiatric disorders.
Neurobiol Stress (2021) 14: 100313. DOI: 10.1016/j.ynstr.2021.100313

Faesel, N., Schünemann, M., Koch, M., Fendt, M.:
Angiotensin II-induced drinking behavior as a method to verify cannula placement into the cerebral ventricles of mice: an evaluation of its accuracy.
Physiol Behav (2021) 232: 113339. DOI: 10.1016/j.physbeh.2021.113339

Harb, M., Jagusch, J., Durairaja, A., Endres, T., Leßmann, V.,Fendt, M.:
BDNF haploinsufficiency induces behavioral endophenotypes of schizophrenia in male mice that are rescued by enriched environment.
Transl Psychiatry (2021) 11: 233. DOI: 10.1038/s41398-021-01365-z

French, T., Israel, N., Düsedau, H., P., Tersteegen, A., Steffen, J., Cammann, C., Topfstedt, E., Dieterich, D.,Schüler, T., Seifert, U., Dunay, I. R.:
The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis.
Frontiers in Immunology (2021) April, Volume 12, Article 619465. DOI: 10.3389/fimmu.2021.619465

Fendt, M., Kreutzmann, J., Jovanovic, T.,
Editorial: Learning safety to reduce fear: recent insights and potential implication.
Behav Brain Res (2021) 411: 113402. DOI: 10.1016/j.bbr.2021.11340

Bicakci, A.O., Tsai, P.L., Kahl, E., Mayer, D., Fendt, M.: 
Dissociative effects of neuropeptide S receptor deficiency and nasal neuropeptide S administration on T-maze discrimination and reversal learning.
Pharmaceuticals (2021) 14: 643. DOI: 10.3390/ph14070643

Becker, A., Helmuth, M., Trzeczak, D., Chindo, B. A.:
Methanol extract of Ficus platyphylla decreases cerebral ischemia induced injury in mice.
Journal of Ethnopharmacology 278 (2021) 114219

Ghelani, T., Montenegro-Venegas, C., Fejtova, A., Dresbach, T.:
Nanoscopical Analysis Reveals an Orderly Arrangement of the Presynaptic Scaffold Protein Bassoon at the Golgi-Apparatus
Mol. Neuroscience (2021), Vol. 14, Article 744034

 

 

2020

Hoffmann-Conaway, S., Brockmann, M. M., Schneider, K., Annamneedi, A., Rahman, K. A., Bruns, C., Textoris-Taube, K., Trimbuch, T., Smalla, K.-H., Rosenmund, C., Gundelfinger, E. D., Garner, C. C., Montenegro-Venegas, C.:
Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice.
eLife (2020);9:e56590. DOI.org/10.7554/eLife.56590

Montenegro‑Venegas, C., Fienko, S., Anni, D., Pina‑Fernandez, E., Frischknecht, R., Fejtova, A.:
Bassoon inhibits proteasome activity via interaction with PSMB4.
Cellular and Molecular Life Sciences (2020). DOI.org/10.1007/s00018-020-03590-z

Montenegro-Venegas, C., Annamneedi, A., Hoffmann-Conawaye, S., Gundelfinger, E. D., Garner, C. C.:
BSN (bassoon) and PRKN/parkin in concert control presynaptic vesicle autophagy. 
Autophagy (2020), DOI: 10.1080/15548627.2020.1801259

Kolodziejczyk, M.H., Fendt, M.:
Corticosterone treatment and incubation time after contextual fear conditioning synergistically induce fear memory generalization in neuropeptide S receptor-deficient mice.
Front Neurosci (2020) 14: 128

Kreutzmann, J.C., Khalil, R., Köhler, J.C., Mayer, D., Florido, A., Nadal, R., Andero, R., Fendt, M.:
Neuropeptide-S-receptor deficiency affects sex-specific modulation of safety learning by pre-exposure to electric stimuli.
Gen Brain Behav (2020) 19: e12621

Kreutzmann, J.C., Fendt, M.:
Chronic inhibition of GABA synthesis in the infralimbic cortex facilitates conditioned safety memory and reduces contextual fear.
Trans Psychiatry (2020) 10: 120. DOI: 10.1038/s41398-020-0788-8.

Wöhr, M., Willadsen, M., Kisko, T.M., Schwarting, R.K.W., Fendt M.:
Sex-dependent effects of Cacna1c haploinsufficiency on behavioral inhibition evoked by conspecific alarm signals in rats.
Prog Neuropsychopharmacol Biol Psychiatr (2020) 99: 109849. DOI: 10.1016/j.pnpbp.2019.109849

Fendt, M., Parsons, M.H., Apfelbach, R., Carthey, A.J.R., Dickman, C.R., Endres, T., Frank, A.S.K., Heinz, D.E., Jones, M.E., Kiyokawa, Y., Kreutzman, J.C., Roelofs, K., Schneider, M., Sulger, J., Wotjak, C.T., Blumstein, D.T.:
Context and trade-offs characterize real-world threat detection systems: A review and comprehensive framework to improve research practice and resolve the translational crisis.
Neurosci Biobehav Rev (2020) 115: 25-33. DOI: 10.1016/j.neubiorev.2020.05.002

Kolodziejczyk, M.H., Faesel, N., Koch, M., Fendt, M.:
Sociability and extinction of conditioned social fear is affected in neuropeptide S receptor-deficient mice.
Behav Brain Res (2020) 393: 112782. DOI: 10.1016/j.bbr.2020.112782 Kreutzmann, J.C., Jovanovic, T., Fendt, M.: Psychopharmacology (2020) 237: 2161-2172. DOI: 10.1007/s00213-020-05527-7

Kreutzmann, J.C., Jovanovic, T., Fendt, M.:
Infralimbic cortex activity is required for the expression but not the acquisition of conditioned safety.
Psychopharmacology (2020) 237:2161-2172

Kaushik, R., Lipachev, N., Matuszko, G., Kochneva, A., Dvoeglazova, A., Becker, A., Paveliev, M., Dityatev., A.:
Fine structure analysis of perineuronal nets in the ketamine model of schizophrenia.
Eur J Neurosci. 2020;00:1-17

Uzuneser, T.C., Fendt, M.:
Individual expression of conditioned safety but not of conditioned relief is correlated with contextual fear. 
Behav Brain Res (2020) 393: 112799. DOI: 10.1016/j.bbr.2020.112799

Cornelius, A.D.A., Hosseini, S., Schreier, S., Fritzsch, D., Weichert, L., Michaelsen-Preusse, K., Fendt, M., Kroeger, A.:
Langat virus infection affects hippocampal neuron morphology and function in mice without disease signs.
J Neuroinflamm (2020) 17: 278. DOI: 10.1186/s12974-020-01951-w

Durairaja, A., Fendt, M.:
Orexin deficiency modulates cognitive flexibility in a sex-dependent manner. 
Genes Brain Behav (2020) e12707. DOI: 10.1111/gbb.12707

Fernández-Orth, J., Rolfes, L., Gola, L., Bittner, S., Andronic, J., Sukhorukov, V. L., Sisario, D., Landgraf, P., Dieterich, D. C., Cerina, M., Smalla, K.-H., Kähne, T., Budde, T., Kovac, S., Ruck, T., Sauer, M., Meuth, S. G.:
A role for TASK2 channels in the human immunological Synapse.
Eur. J. Immunol. (2020) 00: 1–12 DOI: 10.1002/eji.201948269

Letzte Änderung: 11.05.2022 - Ansprechpartner:

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